Some things can’t be unlearned. This is the dawn of posthumanity.

Gleaming labs whir with the hum of servers as scientists unravel the secrets of the universe. But as we peel away mysteries, the universe looks back at us. Even now, terrors rise from the Mariana Trench and drift down from the stars. Scientists are disappearing—or worse. Eldritch algorithms are erected as countermeasures. Experiments take on minds of their own. Some fight back against the unknown, some give in, some are destroyed, and still others are becoming… more. The human and inhuman are harder and harder to distinguish. Mankind is changing, whether it wants to or not, using implants, chemical alterations, genetic manipulation, new senses that man did not evolve to process, artificial intelligence, cybernetics, drugs—brand new ways of thinking.

Of course, the Old Ones laugh at our laws, scientific and otherwise. What havoc is wreaked by those humans trying to harness and control their science to grow as a species? As big science progresses and the very particles and substance of this universe are understood, what stories are being hushed up? Tell us a tale, and make sure it has a beginning, a middle, an end, and a Cthulhu… (Well, incorporate the Cthulhu Mythos, anyway. Big C himself doesn’t need to make an appearance.)